Cerebral amyloid angiopathy
نویسنده
چکیده
Cerebral amyloid angiopathy is increasingly recognized as a major cause of hemorrhagic stroke in the elderly as well as an important contributor to the growing challenge of vascular cognitive impairment, even in cerebral amyloid angiopathy patients without hemorrhagic stroke. Among the advances highlighted in this update are: (1) the importance of sulcal bleeding events in early recurrent hemorrhagic stroke in cerebral amyloid angiopathy; (2) the varied clinical presentations and associated neuroimaging profiles of the disease; (3) the cognitive profile of cerebral amyloid angiopathy; (4) the cumulative importance of different pathologic lesions in cerebral amyloid angiopathy that contribute to cognitive decline and the emergence of techniques to measure this cumulative effect by assessing structural connectivity in the disease; (5) the role of impaired vascular reactivity early in disease course; and (6) the role of vascular amyloid in causing cerebral microbleeds in the disease.
منابع مشابه
Cerebral amyloid angiopathy presenting as a mass lesion.
A rare clinical presentation of cerebral amyloid angiopathy is reported. Our patient presented with the clinical and radiological signs of a right frontal mass lesion suggesting a brain tumor, and a biopsy provided the diagnosis of cerebral amyloid angiopathy. A brief review of the pathology and clinical features of cerebral amyloid angiopathy is presented.
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